IN POUCHES of 30, 60, 120 or 180


SAM-e (S-Adenosylmethionine) is found in every living being. It is derived from the amino acids methionine and ATP (Adenosine Triphosphate). It is concentrated in the liver and brain and has multiple mechanisms of action in the body. 

SAMe is essential to the manufacture of many important brain compounds such as neurotransmitters and phospholipids, which are critical for maintaining healthy mood, emotional well-being and cognitive function.

Various factors such as diet and ageing can cause low levels of SAM-e, leaving you feeling unbalanced and moody.  


Helps replenish your SAM-e levels and promotes a healthy mood. 

SAM-e supports brain function and brain cell neuronal health by boosting levels of neuroprotective compounds L-Glutathione (GSH) & SuperoxideDismutase (SOD). 

SAM-e's ability to both sustain emotional well-being and combat brain ageing has been established by leading universities and medical organisations.


SAM-e is also a naturally occurring compound that is found in almost every tissue and fluid in the body. 

In clinical trials, supplementation of SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue, and reduces sensitivity and stiffness in ageing individuals. SAM-e can stimulate the reproduction of joint connective tissue and improve cartilage function – the key to reversing joint sensitivity and discomfort.


Age, stress, free radicals and environmental conditions can dramatically impact the liver's health and accelerate the ageing process. 

SAM-e helps support healthy levels of glutathione, a critical antioxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidyl-choline and L-cysteine, both necessary for maintaining liver health.


As a diet supplement for adults, take 1 tablet daily in between meals, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.


SAM-e could be dangerous when combined with antidepressants or supplements that treat depression, like St. John's Wort. 

SAM-e could also interact with some prescription painkillers, cough medicines, and treatments for diabetes and Parkinson's disease. 

Patients taking MAOIs should not use SAM-e without discussing it with their doctor. 

High doses of oral SAM-e can cause symptoms like gas, upset stomach, diarrhea, constipation, dry mouth, headache, dizziness, anxiety, and skin rashes. 

SAM-e can also trigger an allergic reaction in some people.

If you have any medical issues, check with a doctor before you start using SAM-e supplements. SAM-e might not be safe for people with conditions such as bipolar disorder, Parkinson?s disease, and diabetes. 

Because SAM-e can affect the blood vessels, stop using SAM-e two weeks before getting surgery. 


S-Adenosyl Methionine 400mg; Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Carboxymethyl Starch Sodium, Hydroxypropyl methyl cellulose, enteric-coating powder. No preservatives. Yeast & Gluten free


Store in a cool, dry place. Keep away from intense light and heat.


If you have a medical condition, are pregnant, lactating, trying to conceive, or taking medications, consult your doctor before use + Do not exceed stated recommended dose + Discontinue and see a doctor if any adverse reactions occur + Do not use if seal is broken + Keep out of reach of children.


GOVITAMINS makes no claims about the diagnosis, treatment or cure of diseases. The content in this text is derived from sources deemed to be accurate and reliable, but no guarantees can be made regarding accuracy or reliability as it is intended for informational purposes only, and should not be construed as medical advice; you are solely responsible for your health and nutritional choices. For further advice, consult a qualified medical doctor, preferably one with knowledge of health supplements.


  GOVITAMINS is a family-run business and dedicated to ensuring that each and every customer receives their order in the most efficient manner with a truly satisfying shopping experience. 
Whilst it is our aim to provide you with the highest quality supplements at unbelievably and continuously low prices, we don't believe you should be taking any supplement unless you take advice from your doctor first, and until you know the full facts about it so that you can judge for yourself if it suits your own, personal, unique circumstances.


We ship orders free of charge. Your item will be carefully packed and dispatched on the same day as purchase – Monday to Saturday (unless you are notified that we are on holiday, when it will be dispatched immediately upon our return). We use Royal Mail 2nd class delivery for all UK deliveries (or ROYAL MAIL SPECIAL DELIVERY if you pay extra for express delivery). For worldwide shipments, we use Royal Mail International International Standard, which has no tracking - or you can pay extra for tracking services. 


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  • If, after buying from us, you CHANGE YOUR MIND and decide that you DO NOT WANT your item, please let us know, and then return it in the original packaging within 60 days. In this scenario, the buyer pays for the return postage, but we will give you a FULL REFUND of the original purchase price you paid – as long as the item is not damaged in any way.
  • Availability: Pre-Order
  • Model: SAM-e
  • Manufacturer: GOVITAMINS